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    • Venereal Disease Research Laboratory test

    Blood test for syphilis

    Medical diagnostic method

    Venereal Disease Research Laboratory test

    VDRL slide for performing the blood test for syphilis

    Purposeblood test for syphilis

    The Venereal Disease Research Laboratory test (VDRL) is a blood test for syphilis and related non-venereal treponematoses that was developed by the eponymous US laboratory.

    The VDRL test is used to screen for syphilis (it has high sensitivity), whereas other, more specific tests are used to diagnose the disease.

    History

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    The VDRL type test was invented before World War I, with its first iteration being that developed by August Paul von Wasserman with the aid of Albert Neisser in 1906.

    The VDRL test, as it is largely still done today, was developed in 1946 by Harris, Rosenberg, and Riedel.[1] The lab was renamed to the Treponemal Pathogenesis and Immunology Branch of the United States Public Health Service.[citation needed]

    Mechanism

    [edit]

    The VDRL is a nontreponemal serological screening for syphilis tha

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